If the sequencer used to generate the ab1 files is Applied Biosystem 3130XL / ABI3130XL: To load a...
Why can some Sanger ab1 files not be read? Is there an alternative, if the base-called sequence is missing (PBAS tag)?
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Alamut™ Visual Plus
Could we install the application on a shared drive, and would it impact the user experience?
It is not recommended to install AlamutTM Visual Plus on a shared drive because of performance...
Can I export external annotation for several variants from AlamutTM Visual Plus?
The export of external annotation is allowed per variant from the Variant Panel or directly from...
How is variant creation in intergenic regions managed, and what causes us to see the message “No nearby genes are available for this query”?
When creating a new variant in an intergenic area, AlamutTM Visual Plus looks for the two closest...
For reverse genes, why is there a difference in the deletion in genomic and transcript annotation? Why is the deletion in a repeat region displayed incorrectly?
AlamutTM Visual Plus applies the internationally recognized HGVS nomenclature. In the case of...
Is it possible to save variants with different transcripts in the same local variant database?
It is not possible to have more than one transcript related to a single variant in the same...
What is the meaning of the colors in the nucleotide conservation track?
The nucleotide conservation track shows scores of evolutionarily conserved nucleotides based on...
Can AlamutTM Visual Plus visualize reads (BAM files) from the SOPHiA DDMTM Whole Exome Sequencing Solution (WES)?
It is possible to click on the “Alamut” button in the SOPHiA DDMTM Platform, or to download BAM...
Why can some transcript versions not be added to the AlamutTM Visual Plus database?
Several RefSeq transcript versions cannot be added to the AlamutTM Visual Plus database, due to...
Why is there a difference in mitochondrial sequences between Alamut Visual and AlamutTM Visual Plus?
This is related to mismatches that can exist between the transcript and reference genome. Alamut...
Do users need access to the SQL database to use AlamutTM Visual Plus?
Users do not have direct access to the AlamutTM Visual Plus database and thus do not need to write...
How is nonsense-mediated mRNA decay (NMD) prediction determined?
In AlamutTM Visual Plus, the limit fixed to trigger NMD is 50 nucleotides.