We are glad to return to Swiss Biotech Day 2025, where you will have the chance to meet our BioPharma and Medical teams for two days of exciting networking, innovation, and insights sharing on the potential of AI-driven solutions to transform precision medicine.

Join us on May 5^th at 16:45 pm, in the Montreal room, for an engaging panel discussion on the transformative role of AI-powered technology in building scalable, high-performance healthcare solutions. Discover how collaboration drives innovation and advances precision medicine.

Harnessing AI & Big Data: The Next Frontier in Biotech and Healthcare

Moderator:

• Pablo Nieto, Principal, EMEA Commercial Excellence & AI/ML Solutions, Generative AI for Consulting, IQVIA

Panelists:

• Tom Baker, SVP and GM Switzerland and Israel, IQVIA
• Philippe Menu, EVP, Chief Medical Officer & Chief Product Officer, SOPHiA GENETICS
• Eva-Maria Hempe, Head of Healthcare and Life Sciences EMEA, NVIDIA
• Erwin Böttinger, Director, Wyss Center for Bio and Neuroengineering

We are thrilled to announce our presence at the 3^rd edition of Artificial Intelligence for Oncology. You will have the chance to meet our BioPharma and Multimodal R&D experts and learn how we help BioPharma companies address challenges throughout the drug development continuum with data solutions tailored to their needs, bringing more effective drugs to the right patients.

If you are attending, don’t miss our talk on Friday, May 9^th at 3.25pm, during the Industry Symposium.

“Accelerating Precision Oncology with Multimodal Data Analytics”
Hamza Boulaala, Data Scientist, Multimodal R&D, SOPHiA GENETICS

Join us in this session to learn how SOPHiA DDM™ for Multimodal is transforming the future of oncology, one breakthrough at a time:

• Discover the AI-powered SOPHiA DDM™ Multimodal Factory for advanced analytics
• Learn how collective intelligence fuels real progress in precision oncology
• Understand the role of strategic technology partnerships in scaling data-driven medicine
• Explore a real case study showcasing how SOPHiA DDM™ transforms multimodal data into predictive insights

We are thrilled to be back at 15^th World Clinical Biomarkers & Companion Diagnostics Summit Europe. Join us and meet our BioPharma team to learn how we help BioPharma companies address challenges throughout the drug development continuum, enhancing efficiency and precision to accelerate the development of better and more effective precision therapeutics.

If you are around, don’t miss our plenary talk on Wednesday, April 9^th from 11.30am to 12.00pm.

New and Innovative Ways to Democratize Precision Medicine Testing​

Jess Lambe, Vice President and Managing Director of BioPharma Business Development, SOPHiA GENETICS

• Learn how to unlock the potential of SOPHiA DDM™ to optimize late-stage clinical development by designing and deploying genomics solutions at scale.
• Gain insights into the regulatory pathway of the SOPHiA DDM™ Platform and its validation path for broadening access to precision therapies.
• Understand SOPHiA GENETICS market-leading lab footprint and ability to truly democratize genomics.
• Hear how SOPHiA GENETICS and AstraZeneca are joining forces to shape healthcare’s future by standardizing and decentralizing a best-in-class liquid biopsy assay on a global scale.

Book a Meeting

SOPHiA GENETICS enables institutions across the globe to launch world-class oncology testing

BOSTON, MA and ROLLE, Switzerland, Feb. 24, 2025 /PRNewswire/ -- SOPHiA GENETICS (Nasdaq: SOPH), a pioneer in AI healthcare technology and a leader in data-driven medicine, announced a new milestone in the global adoption of its groundbreaking cancer testing applications MSK-ACCESS^® powered with SOPHiA DDM™ and MSK-IMPACT^® powered with SOPHiA DDM™. Thirty-seven prominent institutions, including top researchers and key opinion leaders worldwide, have already adopted the recently launched Liquid Biopsy and Solid Tumor applications.

Professor Umberto Malapelle, Chair of the Predictive Molecular Pathology Laboratory at the Department of Public Health of the University Federico II of Naples, Italy and the Scientific Secretary of the International Society of Liquid Biopsy, championed the new applications to support his research on lung and other cancers.

"When I learned SOPHiA GENETICS was offering applications from MSK on the SOPHiA DDM™ platform, I was really interested in the evaluation of the performance of this test, in particular because I see SOPHiA GENETICS as true collaborators to help pave the way for the future of cancer research," said Professor Malapelle.

"Bringing best-in-class technology to global organizations is crucial to help advance better health care for all. We are proud to work with trailblazers like Professor Malapelle, who are utilizing our technology and the collective power of our network to make strides in the next wave of cancer care," said Ross Muken, President, SOPHiA GENETICS.

Of the thirty-seven institutions adopting MSK solutions, thirty-four have signed on to adopt MSK-ACCESS^® powered with SOPHiA DDM™, just ten months after the Liquid Biopsy application's launch. The decentralized deployment of MSK-ACCESS^® has enabled hospitals and labs across the globe to launch world-renowned Liquid Biopsy testing from within the walls of their own institution, providing patients with a less-invasive option for genomic testing. In many cases, this decentralized testing also results in lower costs and faster turnaround times, while also enabling institutions to retain control of their patients' data for research or other purposes.

Internationally recognized organizations adopting the application include: Heidelberg University Hospital in Germany; Biopticka Laboratory in the Czech Republic; Hospital del Mar and Hospital La Fe in Spain; University Hospital of Nice and Marseille Regional Hospital Center in France; and Jewish General Hospital in Canada.

The complementary solid tumor application, MSK-IMPACT^® powered with SOPHiA DDM™, has also attracted significant interest from leading organizations across the globe, including: the Jiménez Díaz Foundation University Hospital in Spain; the Cyprus Institute of Neurology and Genetics in Cyprus; and Sofiva Genomics in Taiwan.

Memorial Sloan Kettering Cancer Center (MSK) and SOPHiA GENETICS partnered in 2023 with a vision to use the sophisticated technology of the SOPHiA DDM™ Platform to bring MSK's state-of-the-art cancer testing capabilities to precision medicine institutions worldwide. The two leaders launched the Liquid Biopsy test MSK-ACCESS^® powered with SOPHiA DDM™ in April 2024. In October 2024, SOPHiA GENETICS announced a definitive partnership agreement with AstraZeneca (LSE/STO/Nasdaq: AZN) to accelerate the deployment of MSK-ACCESS^® powered with SOPHiA DDM™, aiming to increase the availability of this innovative Liquid Biopsy solution worldwide. In November 2024, SOPHiA GENETICS announced the launch of the complementary Solid Tumor test, MSK-IMPACT^® powered with SOPHiA DDM™. These collaborations have the potential to transform cancer research as they enable healthcare providers to draw from a continuously evolving base of real-world data and gain insights from diverse populations while using best-in-class technology.

Join us on Tuesday, February 25, 2025, at 11:00 a.m. (11:00) EDT / 5:00 p.m. (17:00) CET for the Precision Oncology Showcase, a virtual webinar which will spotlight the transformative potential of decentralized, AI-driven technologies for the advancement of cancer care.  

About SOPHiA GENETICS
SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native healthcare technology company on a mission to transform patient care by expanding access to data-driven medicine globally. It is the creator of the SOPHiA DDM™ Platform, which analyzes complex genomic and multimodal data and generates real-time, actionable insights for a broad global network of hospital, laboratory, and biopharma institutions. For more information, visit SOPHiAGENETICS.com and connect with us on LinkedIn.

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact support@sophiagenetics.com to obtain the appropriate product information for your country of residence. 

Memorial Sloan Kettering (MSK) has institutional financial interests related to SOPHiA GENETICS.

Forward-Looking Statements
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding SOPHiA GENETICS future results of operations and financial position, business strategy, products and technology, partnerships and collaborations, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on SOPHiA GENETICS' management's beliefs and assumptions and on information currently available to the company's management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in the company's filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of its date. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in the company's expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

For further information: Media Contact: media@sophiagenetics.com

The cutting-edge OncoPortal™ Mutation Tracker add-on module enables precision monitoring of evolving genomic cancer drivers

Boston, MA and Rolle, Switzerland, January 28, 2025 – SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native healthcare technology company and a global leader in data-driven medicine, has unveiled the OncoPortal™ Mutation Tracker— a longitudinal MRD tracking tool designed for disease monitoring in the context of oncology. This innovation underscores SOPHiA GENETICS’ commitment to advancing data-driven approaches for improved oncology insights.

Tracking genomic variants across multiple time points in the same patient is becoming increasingly critical in cancer care, particularly for identifying treatment resistance or detecting residual cancer cells, such as in Measurable Residual Disease (MRD) management. The integration of longitudinal tracking capabilities with next-generation sequencing (NGS) allow the parallel detection of cancer-specific genetic mutations at very low frequencies. This combined approach enables early identification of residual disease or emerging variants, providing a more precise assessment of disease burden, better stratification of high-risk patients, and the ability to tailor treatments to the cancer’s unique genomic profile.

The OncoPortal™ Mutation Tracker augments the SOPHiA DDM™ Platform’s core analytical capabilities to allow clinical researchers to longitudinally monitor evolving genomic variants across multiple time points, providing a comprehensive view of disease evolution. The OncoPortal™ Mutation Tracker enhances workflow efficiency for longitudinal variant tracking by offering flexible low frequency variant selection, customizable threshold settings, and reporting features to generate longitudinal graphical representations, simplifying the process of tracking and analyzing genetic changes over time.

“The ability to reliably track low frequency variants longitudinally is a game-changer because it allows the detection of even the smallest traces of cancer that can evade traditional methods of testing and ultimately drive relapse,” said Philippe Menu, M.D., Ph.D., Chief Medical Officer and Chief Product Officer, SOPHiA GENETICS. “With this new longitudinal tracking capability, we offer a highly customizable, user-friendly solution to enable the generation of novel insights for clinical research. Precise tracking of key genomic variants over time has the potential to eventually enable earlier intervention and more tailored disease management, which may lead to better long-term outcomes for patients.”

“This longitudinal interface represents the solution we've been seeking to unite our oncologists in embracing broader adoption of NGS. It's the missing piece that unlocks a new frontier in personalized, data-driven medicine,” said Dr. Christophe Marzac Head of the Hematology-Immunology Unit Gustave Roussy Institute.

For more information on the OncoPortal™ Mutation Tracker, visit SOPHiAGENETICS.com.

About SOPHiA GENETICS 

SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native healthcare technology company on a mission to transform patient care by expanding access to data-driven medicine globally. It is the creator of the SOPHiA DDM™ Platform, which analyzes complex genomic and multimodal data and generates real-time, actionable insights for a broad global network of hospital, laboratory, and biopharma institutions. For more information, visit SOPHiAGENETICS.com and connect with us on LinkedIn.

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact support@sophiagenetics.com to obtain the appropriate product information for your country of residence. 

SOPHiA GENETICS Forward-Looking Statements:

This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements. 

Media Contact: 

Kelly Katapodis
media@sophiagenetics.com

We are excited to be back at ECP in 2025! Join us and explore more about our recent developments in Liquid Biopsy, CGP, Solid Tumors and more!

SOPHiA GENETICS is thrilled to be back at ESHG 2025! Come meet our team to learn how SOPHiA GENETICS can help turn complex generic data into life-changing Insights! 

SOPHiA GENETICS is thrilled Charité Mayo Conference 2025! Visit us to learn how we advance data-driven medicine, with our cloud-based SOPHiA DDM™ Platform. Discover how it empowers health data interpretation with advanced analytics modules, simplified reporting, and a global community of healthcare institutions.  

Join us at the 14th International Symposium on Minimal Residual Cancer (ISMRC) in Nice, France, where experts gather to explore the latest advancements in liquid biopsy. Discover how SOPHiA GENETICS is transforming cancer care through innovative solutions at the forefront of precision oncology. Visit our booth to learn more and connect with our team—see you there! 

SOPHiA GENETICS™ is thrilled to return for Festival of Genomics! Visit us at booth #91 to learn more about the New Generation SOPHiA DDM™ Platform and Alamut™ Visual Plus.